Mesenchymal stem cells: Emerging mechanisms of immunomodulation and therapy
نویسندگان
چکیده
منابع مشابه
Immunomodulation by Mesenchymal Stem Cells
Mesenchymal stem cells (MSCs) are pluripotent stromal cells that have the potential to give rise to cells of diverse lineages. Interestingly, MSCs can be found in virtually all postnatal tissues. The main criteria currently used to characterize and identify these cells are the capacity for self-renewal and differentiation into tissues of mesodermal origin, combined with a lack in expression of ...
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Mesenchymal stem cells (MSCs) possess immunomodulatory properties, which confer enormous potential for clinical application. Considerable evidence revealed their efficacy on various animal models of autoimmune diseases, such as multiple sclerosis, systemic lupus erythematosus and uveitis. MSCs elicit their immunomodulatory effects by inhibiting lymphocyte activation and proliferation, forbiddin...
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Colorectal Cancer (CRC) is the third most common cancer and the second leading cause of cancer-related death all around the world with an estimated 1.2 million new cases and a half million deaths each year. Although some curing methods such as surgery and chemotherapy are used in the early stage of CRC, targeted therapy is one of the principal modes of cancer treatment that could be a reliable ...
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Mesenchymal stem cells (MSCs) as a kind of adult stem cells possess two properties of long term selfrenewal ability and multilineage differentiation potential into skeletal cell lineages. MSCs were first isolated and described from bone marrow samples. Further investigations have identified several other tissues as alternative sources for these cells. In spite of the clinical importance of MSCs...
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ژورنال
عنوان ژورنال: World Journal of Stem Cells
سال: 2014
ISSN: 1948-0210
DOI: 10.4252/wjsc.v6.i5.526